Tuesday, April 14, 2015

In Memory Of

I have added several persons, some of them friends and some family of friends to my In Memory Of page. Please visit it and pay your respects. If you know anyone on the page who is listed by name only and have a picture of them, I would appreciate it. There is an email form on the bottom of my blog right hand side. Paying proper respect to these people is utmost in my heart. Thank You.

God Bless & Keep You & This Country of Ours!
joe

PS: if there is someone you want to honor that died from any form of dementia, feel free to send their name, birth year, year set free and a picture if possible.

Tuesday, March 31, 2015

Alzheimer's and me!

My old friend Alzheimer's has been hugging me more tightly these days. Guess the old bugger just cannot get enough of me.  I find that conversations are very different from what I now hear. Seems to be getting harder to talk with folks. Once I am on a roll it is ok, but let something interrupt me and who the hell knows where I am then. I am getting testier with those around me, just have to sometimes cannot keep it in. Hidding my wonderfull world of dementia does not work to well anymore, but I guess that is the way it is to be. Have been reading about some of the simillairities between Lewy Bodies and Parkinson's.  Now I understand why Parkinson's is a form of dementia.

Well is it Alzheimer's or Schizophrenia??
My doc thinks I am a bit schizo and has for years.  Maybe it is not Alzheimer's or Schizophrenia, could be Alzhphrenia a new type of dementia. The following is an interesting look into the brain.


Brain's dementia weak spot identified

  • 25 November 2014
  •  
  • From the sectionHealth
Conceptual computer artwork depicting neurology. From left to right: MRI brain scans, 3D dsi white matter brain scan, brain, Alzheimer's brain versus normal brain, MRI brain scan
The brain has a weak spot for Alzheimer's disease and schizophrenia, according to UK scientists who have pinpointed the region using scans.
The brain area involved develops late in adolescence and degenerates early during ageing.
At the moment, it is difficult for doctors to predict which people might develop either condition.
The findings, in the journal PNAS, hint at a potential way to diagnose those at risk earlier, experts say.
Although they caution that "much more research is needed into how to bring these exciting discoveries into the clinic".

Weak spot

The Medical Research Council team who carried out the study did MRI brain scans on 484 healthy volunteers aged between eight and 85 years.
The researchers, led by Dr Gwenaƫlle Douaud of Oxford University, looked at how the brain naturally changes as people age.
The images revealed a common pattern - the parts of the brain that were the last to develop were also the first to show signs of age-related decline.
These brain regions - a network of nerve cells or grey matter - co-ordinate "high order" information coming from the different senses, such as sight and sound.
When the researchers looked at scans of patients with Alzheimer's disease and scans of patients with schizophrenia they found the same brain regions were affected.
The findings fit with what other experts have suspected - that although distinct, Alzheimer's and schizophrenia are linked.
Prof Hugh Perry of the MRC said: "Early doctors called schizophrenia 'premature dementia' but until now we had no clear evidence that the same parts of the brain might be associated with two such different diseases. This large-scale and detailed study provides an important, and previously missing, link between development, ageing and disease processes in the brain.
"It raises important issues about possible genetic and environmental factors that may occur in early life and then have lifelong consequences. The more we can find out about these very difficult disorders, the closer we will come to helping sufferers and their families."
Dr Michael Bloomfield of University College London said: "Schizophrenia can be potentially devastating but at the moment it's very difficult to predict with certainty who is going to have a good prognosis and who might have a poor one.
"This study brings us a step closer to being able to make this prediction, so patients could in the future receive better targeted treatments."
Armed with this new knowledge, it may also be possible to understand how to prevent the brain changes before they occur, he said

More on this story

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God Bless & Keep You & This Country of Ours!
joe

Tuesday, March 17, 2015

Disconnect between brain and fingers.

Hi to All!

I have not posted alot lately regarding me and my journey with Alzheimer's. I am starting to have great difficulty in getting what is in my brain cell to my fingers. Somewhere on it's journey from brain to fingers it gets lost or just plain nothing. I have been fortunate for sometime to be able to communicate here with all of you. But it seems the disease is starting to take what it feels rightfully belongs to it. It is taking a physical toll on me as well. Greedy bastard that it is. I do not write much about going here or there, because I feel that my mission on this blog is to talk about what the disease really does.
Once again I have started getting this crap on how to prevent Alzheimer's or dementia in and of it self. How to cure it. Boils down to the same old bullshit nothing. The new studies and trials that promise so much, suddenly you stop hearing about them, why because they all fail. To many restrictions on reasearch and movement of possible drugs to the market. Smaller brained powered individuals then myfelf  making life decisions for you and me, makes no sense.
I guess 57+ people dieing each day from the Alzheimer's is of no importance to those that try to govern our lives and tell us how they will take care of us. I say stick it up your already clogged lower intestine. We need to force the issue. Not by kissing up to them, but getting on the unemployment lines and start our revolution to first an understanding of the cause, then how to prevent it where we can (if that is possible), find real treatments that work and not just mask symptoms until they stop and leave the person hanging on the cliff. Sounds a bit political, right? Well the time has come for us to go into action. It is clear those claiming to help us, really have not come much more than a foot in well over 100 years.

God Bless & Keep You & This Country of Ours!
joe

Sunday, March 01, 2015

From Alzheimer's & Dementia Weekly.

FEBRUARY 18, 2015

What is Vascular Dementia?

Vascular dementia is one of the 3 leading causes of dementia. When it appears together with Alzheimer's disease, which it does quite often, it is called "Mixed dementia". Learn what causes it and how to identify different types.



Vascular Dementia and Vascular Cognitive Impairment


Vascular dementia and vascular cognitive impairment (VCI) are caused by injuries to the vessels supplying blood to the brain. These disorders can be caused by brain damage from multiple strokes or any injury to the small vessels carrying blood to the brain. Dementia risk can be significant even when individuals have suffered only small strokes. Vascular dementia and VCI arise as a result of risk factors that similarly increase the risk for cerebrovascular disease (stroke), including atrial fibrillation, hypertension, diabetes, and high cholesterol. Vascular dementia also has been associated with a condition called amyloid angiopathy, in which amyloid plaques accumulate in the blood-vessel walls, causing them to break down and rupture. Symptoms of vascular dementia and VCI can begin suddenly and progress or subside during one’s lifetime.

Some types of vascular dementia include:

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). This inherited form of cardiovascular disease results in a thickening of the walls of small- and medium-sized blood vessels, eventually stemming the flow of blood to the brain. It is associated with mutations of a specific gene called Notch3, which gives instructions to a protein on the surface of the smooth muscle cells that surround blood vessels. CADASIL is associated with multi-infarct dementia, stroke, migraine with aura (migraine preceded by visual symptoms), and mood disorders. The first symptoms can appear in people between ages 20 and 40. Many people with CADASIL are undiagnosed. People with first-degree relatives who have CADASIL can be tested for genetic mutations to the Notch3 gene to determine their own risk of developing CADASIL.

Multi-infarct dementia. This type of dementia occurs when a person has had many small strokes that damage brain cells. One side of the body may be disproportionally affected, and multi-infarct dementia may impair language or other functions, depending on the region of the brain that is affected. Doctors call these “local” or “focal” symptoms, as opposed to the “global” symptoms seen in AD that tend to affect several functions and both sides of the body. When the strokes occur on both sides of the brain, however, dementia is more likely than when stroke occurs on one side of the brain. In some cases, a single stroke can damage the brain enough to cause dementia. This so-called single-infarct dementia is more common when stroke affects the left side of the brain—where speech centers are located—and/or when it involves the hippocampus, the part of the brain that is vital for memory.

Subcortical vascular dementia, also called Binswanger’s disease. This is a rare form of dementia that involves extensive microscopic damage to the small blood vessels and nerve fibers that make up white matter, the “network” part of the brain believed to be critical for relaying messages between regions. The symptoms of Binswanger’s are related to the disruption of subcortical neural circuits involving short-term memory, organization, mood, attention, decisionmaking, and appropriate behavior. A characteristic feature of this disease is psychomotor slowness, such as an increase in the time it takes for a person to think of a letter and then write it on a piece of paper.

Other symptoms include urinary incontinence that is unrelated to a urinary tract condition, trouble walking, clumsiness, slowness, lack of facial expression, and speech difficulties. Symptoms tend to begin after age 60, and they progress in a stepwise manner. People with subcortical vascular disease often have high blood pressure, a history of stroke, or evidence of disease of the large blood vessels in the neck or heart valves. Treatment is aimed at preventing additional strokes and may include drugs to control blood pressure.

older coupleMixed Dementia


Autopsy studies looking at the brains of people who had dementia suggest that a majority of those age 80 and older probably had “mixed dementia,” caused by both AD-related neurodegenerative processes and vascular disease-related processes. In fact, some studies indicate that mixed vascular-degenerative dementia is the most common cause of dementia in the elderly. In a person with mixed dementia, it may not be clear exactly how many of a person’s symptoms are due to AD or another type of dementia. In one study, approximately 40 percent of people who were thought to have AD were found after autopsy to also have some form of cerebrovascular disease. Several studies have found that many of the major risk factors for vascular disease also may be risk factors for AD.

Researchers are still working to understand how underlying disease processes in mixed dementia influence each other. It is not clear, for example, if symptoms are likely to be worse when a person has brain changes reflecting multiple types of dementia. Nor do we know if a person with multiple dementias can benefit from treating one type, for example, when a person with AD controls high blood pressure and other vascular disease risk factors.

See More Vascular Dementia Videos and Articles

Monday, February 09, 2015

Women make up 72 per cent of Alzheimer's patients in Canada | CTV News

Women make up 72 per cent of Alzheimer's patients in Canada | CTV News:



'via Blog this'



Ok ladies which is it your Brain or your chest? I know I sound like a broken record but us with Alzheimer's tend to repeat ourselves alot.



God Bless,

joe

Saturday, January 24, 2015

I am sure this will piss off many.

I am sure this will piss off many. But kiss my ass. For years I have been trying my damndest  to get something done for us that suffer one or another form of Dementia, you know the killer with millions and no survivors.

So one transgender girl goes out and steps in front of a truck and commits suicide and the world suddenly says OOOOOH these people need help. Amazon.com in tribute to her is offering new customers Prime for one yea at $72.00 in her honor. Well fuck me please.

I can understand her wanting to leave a life that is fucked up for her. See I feel the same about mine, but when I expressed that feeling in an HBO documentary The Alzheimer's Project, you can find a link to it on my blog, I was chastised by I cannot tell you how many people. It is a wonderful and selfless act she has preformed to bring attention to her plight, but for me to do the same thing OH NO, i am selfish, I would run family lives, etc. Well what the hell did she do.

This is not a shame on her post, I understand her wanting to leave a life she could nolonger live in or function in. I feel that pain daily and have for 10 years. This is a SHAME on YOU post for not helping us that are dying daily from our disease. Yes all the so called Alzheimer groups out there and our government who cannot get their heads out of their asses.

Leelah Alcorn is now free of her torment. May God keep her close and wrapped in his arms, I for one feel the pain she had. I have now found out that that I have vascular calcification taking place in my muscle tissue in both my kneck and spine, oooh goody now I am a real hard head. This only leads to stroke, death and if I am truly lucky Vascular Dementia, I will have a trifecta, Alzheimer's, Frontal Temporal Dementia and Vascular Dementia.  Is it ok with you now if i still am considering setting my self free?

NOW WHEN DO YOU ALL GET OFF YOUR FLAT BUTTS AND HELP US? 

God Bless & Keep You & This Country of Ours!
joe